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This mixed cellulose ester (MCE) membrane filters are composed of cellulose acetate and cellulose nitrate. MCE membrane filters are suitable for water solution and has low protein sorption. It has high flow rate and high thermal stability, and can remove the bacteria almost 100%. It is an ideal choice for protein and enzyme filtrations, tissue culture media sterilisation, cold sterilisation, biological fluid filtration and other filtration applications. It is not compatible with some organic solvents.